tRNA
is most widely used as the primer of retroviral reverse transcriptases. The 3’
end of the tRNA binds to the complementary binding site on the viral RNA
therefore initiating reverse transcription.
-
tRNALys3
is the primer of HIV-I, HIV-II, SIV and FIV.
-
tRNALys1,2
are the primers of
BLV, HTLV-I and II, SSV, FLV, VV, CAEV, MPMV, SMR and EIAV.
-
tRNATrp
and tRNAPro are the primers of
ASNV, SSV, FLV, BLV, MLV, HTLV-I and II.
Since it has been well documented that artificial tRNA does not posses the same
biological properties as natural tRNA, human purified tRNAs are largely in
demand for retroviral research, especially HIV related research.
The
extraction and purification of tRNA from a natural source such as human
placenta is a highly complicated and delicate
procedure. Bio S&T Inc is the only commercial provider
of highly purified human tRNAs.
Product Description
|
Cat. #
|
Unit Size
|
tRNALys3,
pure
Source: Human placenta
Purity: HPLC grade
|
BH101
|
1
mg
|
tRNALys1,2,
pure
Source: Human placenta
Purity: HPLC grade
|
BH102
|
1
mg
|
tRNALys,
partial
Source: Human placenta
Purity: DEAE grade
|
BH103
|
10
mg
|
tRNAPro,
pure
Source: Human placenta
Purity: HPLC grade
|
BH201
|
1
mg
|
tRNAPro,
partial
Source: Human placenta
Purity: DEAE grade
|
BH202
|
10
mg
|
tRNATrp,
pure
Source: Human placenta
Purity: HPLC grade
|
BH301
|
1
mg
|
tRNATrp,
partial
Source: Human placenta
Purity: HPLC grade
|
BH302
|
10
mg
|
Total
tRNA
Source: Human placenta
|
BH401
|
100
mg
|
|
|
BH501
|
1,000
U
|
|