Meet Bio S&T A foreword by our CEO Upcoming conferences BAC library expertise 3 options BAC sequencing RFQ cDNA and DNA libraries Lambda cDNA/genomic Plasmid cDNA/genomic Normalized cDNA RFQ   Gene synthesis Deliverables and guarantees RFQ Mutagenesis Deliverables and guarantees RFQ DNA sequencing Individual sequencing PCR products END EST clones Whole genome Technology portfolio Drug screening APA technology Sequencing technology APAgene GOLD Walking Kits Retroviral products Other custom services Contact info Site map   Bio S&T Inc. is delighted to offer site-directed mutagenesis: Description Price US Any combination of mutations within a 5 base-frame; $399 Any combination of mutations within a 10 base-frame; $499   IMPORTANT! A SIGNIFICANT volume discount is applicable to large orders. Pease inquire! Our pricing structure depends on location. For example: ATCGG : 1 mutation within a 5-base frame = $399 ATCGG : 4 mutations within a 5-base frame = $399 ATCGGTGGAT : 8 mutations within a 10-base frame = $499 ATCGGTGGAT : 2 mutations within a 10-base frame = $499 ATCGGTGGATCA : 2 mutations, each within a 5-base frame = $399 x 2 We will: perform the site-directed mutagenesis and subsequent sequence verification; provide purified plasmid DNA and E.coli stab; provide chromatogram picture. Please provide us with 2 micrograms of plasmid DNA with the target sequence, sequencing information, plasmid map, and last but not least, target sites for mutations! Plasmid must be less than 8Kb. Please inquire for larger constructs.   To submit your mutagenesis project details please contact us or request a quote on-line! Should you be interested in introducing changes in large constructs, please contact us.